We examined the interplay of Perceived Emotional Intelligence (PEI) and cultural factors in the prediction of Emotional Adjustment. We predicted that PEI influences on Emotional Adjustment are moderated by culture. Culture factors used in this study were Individualism-Collectivism and Masculinity-Femininity scores in Hoftede´s dimensions. Participants from three different cultures (US, Chile, and Spain) completed measures of Perceived Emotional Intelligence TMMS, with three factors: Attention, Clarity, and Repair) and Emotional Adjustment (anxiety and depression). Aspects of Perceived Emotional Intelligence (Clarity and Repair) were associated to a higher level of Emotional Adjustment in all cultures. As predicted, Clarity and Repair were a stronger predictor of Emotional Adjustment in feminist than in masculinity cultures. The results indicate that PEI effects on Emotional Adjustment are moderated by culture.